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PVC pipes exhibit excellent resistance to a wide range of chemical reagents in temperatures up to 50°C. PVC pipes can be used indoors or to transport chemicals or waste products without risk of materials eating through the pipe.

In general, PVC pipes are suitable to convey most strong acids, alkalies and aqueous solutions (except those which are strongly oxidising), aliphatic hydro carbons, fluorides, photographic and plating solutions, brine, mineral oils, fats and alcohols. PVC pipes should not normally be used with aldehydes and ketones, ethers, cyclic ethers, esters and aromatic and chlorinated hydrocarbons, nitro compounds, some petrol / benzene mixtures and similar solvents which lead to a marked swelling and softening of the material.

PVC pipes are widely used in the chemical industry as a piping system for dangerous liquids.